Vitamin D: An Update At A Glance

Several posts have explained the role of vitamin D in immunity and and thus the Covid virus – (can search on this blog under Infectious Disease). This post is simply an update about the expanded role of vitamin D status.

WHAT You Need to Know Vitamin’s Immune Benefits

More than 70% of Americans have insufficient blood levels of vitamin D.

Vitamin D supports the immune system’s response to illnesses of all kinds which may include COVID-19.

Past studies show that low levels of vitamin D are associated with increased rates and severity of viral infections.

Clinical trials have shown that vitamin D has a protective effect against respiratory tract infections.

Vitamin D and Viral Illness

Vital respiratory tract infections, such as flu, are more common during winter. One of the reasons for this may be seasonal variations in our vitamin D levels. During winter, we get less sun, leading to lower vitamin D production. That puts us at increased risk for viral infection. Low vitamin D is also a risk for more severe lung disease called acute respiratory distress syndrome (ARDS). This condition can lead to what is called a cytokine storm with hyper- production of inflammatory factors that can lead to death.

Vitamin D’s Protective Action

Vitamin D contributes to many functions that help shield the body from infections and lessen their severity. Maintaing adequate levels of vitamin D:

Interferes with the ability of viruses to replicate and produce more viral particles.

Helps support and repair heathly cellular linings in the body, including the airways of the lungs.

Increases production of proteins that shield against bacteria and viruses, enhancing the ability of cells to protect themselves from infection.

Improves the ability of immune cells to mount an effective attack against specific viruses.

Helps prevent the immune system from going overboard and producing excessive pro-inflammatory compounds in the lungs.

Summary:

Unfortunately, vitamin D is found naturally in few foods in the diet. These are fish and seafood, fortified breakfast cereals, orange juice, regular milk, rice milk, soy milk, yogurt, and margarine Therefore, an oral supplement may be necessary. If you think you may not get enough D in your diet, please see your physician to discuss the benefits and side effects of vitamin D supplementation. There is a common blood test that he/she may suggest to indicate your blood level of this fat-soluble vitamin.

The Upper Limit is 100 mcg or 4,000 UL if you choose to take a supplement. Consequences of overdose may include: mental retardation in young children, abnormal bone growth and formation, nausea, diarrhea, irritability, weight loss, calcium deposition in organs such as kidneys, liver, and heart, toxicity is possible with long-term use of 10,000 daily.

Nutrition Now, Judith E. Brown, 7th Edition, 2013

Life Extension November, 2020

The Nutritional State of the Nation: Does it Affect Covid-19?

A number of diseases and disorders share common risk factors of low intakes of vegetables, fruits, and whole grains, excess calorie intake, body fat, and high animal fat intake. These risk factors are associated with the development of chronic inflammation and oxidative stress, conditions that are strongly related to the development of heart disease, diabetes, osteoporosis, Alzheimer’s disease, cancer and other chronic diseases that include stroke, osteoporosis, and obesity.

Metabolic syndrome is a cluster of at least three of five conditions: hypertension, high blood sugar, obesity, high triglycerides, and low HDL cholesterol that increase the risk for cardiovascular disease. These diseases are all related to our diets and other lifestyle factors – namely exercise and smoking habits.

A new study in the journal Diabetes Care is the first to look at the impact of metabolic syndrome on outcomes for Covid-19 patients. “Together, obesity, diabetes and prediabetes, high blood pressure and abnormal cholesterol levels are all predictors of higher incidences of death in these patients and were more than three times more likely to die from the disease.

“The more of these diagnoses that you have, the worse the outcomes”, says lead author Joshua Denson , assistant professor of medicine and pulmonary and critical care medicine physician at Tulane University of Medicine.

“The underlying inflammation that is seen with metabolic syndrome may be the driver that is leading to these more severe cases.” Dr. Denson adds.  In this study, the most common conditions were hypertension (80%), obesity (65%), diabetes (54%), and low HDL (39%.)

Dr. Denson would advise anyone who meets the criteria for metabolic syndrome to be vigilant in taking measures to reduce risk or exposure to the coronavirus.  “It doesn’t matter if you’re young or old, we took that into account” he says.

 

 

 

 

 

 

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Chronic Inflammation: Understanding the “Cytokine Storm”

The leading causes of death among Americans are slow developing, lifestyle-related chronic diseases. This includes diabetes, heart disease,  stroke, cancer, hypertension or high cholesterol levels. Diet can often be (but not always) the underlying condition reflected as obesity.  Obesity is now considered to be a major risk factor for complications of COVID-19 infections.

A previous post  explains the role of diet in this occurrence. The post was written before the  co-morbidities   (underlying conditions) were associated with inflammation and severe COVID infections. The following well written article was initially published in The Conversation and succinctly explains how the role of inflammation can contribute to severe COVID and death often described as the “cytokine storm”.

CLICK HERE.