In the News: Keto diets and cancer?

Medical News Today:

New research explores the benefits of keto diets for reversing colorectal cancer in mice.

“Colorectal cancer (CRC) is reported to be the third most common cancer diagnosed in the United States. Studies have shown that high-sugar diets, and excessive consumption of animal protein — especially red meat — increase CRC risk.

On the other hand, studies show that diets involving fasting and caloric restriction are against intestinal tumors in animal models. Whether they may translate over to humans remains unknown.

Recently, researchers conducted a series of mouse studies investigating the underlying protective mechanisms behind a low-carb diet for CRC. A new study demonstrated in a mice model that it prevents colorectal cancer by activating a growth slowing receptor which is found in the lining of the bowel. This receptor may play an important role in preventing cell growth within the intestine,”

Understanding more about the mechanisms underlying the effects of various diets on tumor growth could help researchers develop treatments and preventative options for CRC.

The new study was published in.

Dmitrieva-Posocco, O., Wong, A.C., Lundgren, P. et al. β-Hydroxybutyrate suppresses colorectal cancer. Nature 605, 160–165 (2022). https://doi.org/10.1038/s41586-022-04649-6

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