Most people have never heard of NAFLD, a.k.a. non-alcoholic fatty liver disease, HOWEVER, nearly one in four adults in the U.S. has NAFLD. NAFLD is more common in obesity and diabetes type 2.
In the long term, NAFLD can cause fibrosis (scarring) of the liver that eventually can cause impairment of normal liver function. Advanced scarring can lead to cirrhosis, an irreversible condition that can lead to liver failure. The only long-term treatment is a liver transplant. No drugs are currently approved to treat it.
The emphasis should then be on prevention with the usual recommendations: Eat less processed foods, lose a little weight if necessary, and more exercise comes to mind – healthier lifestyles in general, e.g. less alcohol.
Normally most of the blood draining from the GI tract (gut) travels directly to the liver before entering general circulation. This exposes the liver to toxins that may cause oxidative stress and chronic inflammation.
There are new clinical trials on subjects diagnosed with NAFLD to investigate the influence of probiotics on the microbiome residing in the GI tract. These findings suggest that the probiotic – prebiotic blends can stop the progression of liver disease, liver damage and liver inflammation when compared to a placebo. Interesting???
Richard Moore. Life Extension: The Science of a Healthier Life, May, 2022.