Pre Diabetes and Cognitive Decline

In the News

Pre diabetes linked to cognitive decline

“People with higher than normal blood sugar called prediabetes, are more likely to experience cognitive decline and vascular dementia according to a study published in Diabetes, Metabolism, and Obesity.  

Researchers analyzed UK biobank data from almost 450,000 people averaging 58 years old who underwent an HB A1C test, which determines average blood sugar levels over the past two to three months.

Based on these results, they were divided into one of five groups:  low normal blood sugar, normal blood sugar, pre diabetes, undiagnosed diabetes, and diabetes. Pre diabetes was classified as having a hemoglobin A1C blood test reading of 6.0% – 6.5% %. Ideal A1C levels are under 5.5%

Results show that people with above normal sugar levels were:

42% more likely to experience cognitive decline over four years and 54% were more likely to develop vascular dementia over eight years. Vascular dementia is caused by reduced blood flow to the brain.

People with prediabetes and diabetes had similar rates of cognitive decline, 42% and 39% respectively.

MRI brain scans revealed that pre diabetes was associated with a smaller hippocampus and more strongly associated with having lesions on the brain, both of which are associated with age related cognitive impairment.”

Diabetes is thought to be prevented by making some easy lifestyle adjustments in diet and exercise, in other words a diet that restricts refined carbohydrates, sweetened drinks (including fruit juice) and keeping your weight at a reasonable level with more emphasis on the lower carbohydrate side (less than 40 percent of total calories.) Please consult with your physician before you begin any calorie restricted diet, however.

Source: Diabetes Obes Metab. 2021; 1-10.

Life Extension, May 2021

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.