Tag: emulsifiers

In the News – Pre-Diabetes

Pre diabetes linked to cognitive decline

“People with higher than normal blood sugar called prediabetes, are more likely to experience cognitive decline and vascular dementia according to a study published in Diabetes, Metabolism, and Obesity.  

Researchers analyzed UK biobank data from almost 450,000 people averaging 58 years old who underwent an HB A1C test, which determines average blood sugar levels over the past two to three months.

Based on these results, they were divided into one of five groups:  low normal blood sugar, normal blood sugar, pre diabetes, undiagnosed diabetes, and diabetes. Pre diabetes was classified as having a hemoglobin A1C blood test reading of 6.0% – 6.5% %. Ideal A1C levels are under 5.5%

Results show that people with above normal sugar levels were:

42% more likely to experience cognitive decline over four years and 54% were more likely to develop vascular dementia over eight years. Vascular dementia is caused by reduced blood flow to the brain.

People with prediabetes and diabetes had similar rates of cognitive decline 42% and 39% respectively.

MRI brain scans revealed that pre diabetes was associated with a smaller hippocampus in the brain and more strongly associated with having lesions on the brain, both of which are associated with age related cognitive impairment.”

Editor’s note: ‘Previous research has found a link between poor cognitive outcomes and diabetes, but our study is the first to investigate how having blood sugar levels that are relatively high but do not yet constitute diabetes – may affect our brain health”

Source: Diabetes Obes Metab. 2021; 1-10.

Life Extension, May 2021

Food Additives and the Metabolic Syndrome

 

What is the metabolic syndrome?

The metabolic syndrome is cluster of conditions that increase the risk of heart disease, stroke, and diabetes.

Metabolic syndrome includes high blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol levels. The syndrome increases a person’s risk for heart attack and stroke. Weight loss, exercise, a healthy diet, and smoking cessation can help. Medications may also be prescribed.

In the current study presented, the results support the emerging concept that perturbed host–microbiome interactions resulting in low-grade inflammation can promote obesity and its associated metabolic effects. Moreover, they suggest that the broad use of emulsifying agents might be contributing to an increased societal incidence of obesity/metabolic syndrome and other chronic inflammatory diseases.

Emulsifiers as a food additive act as detergents to  reduce stickiness, control crystallization and prevent separation. They are commonly used in many processed foods such as mayonnaise, ice cream, peanut butter, chocolate, salad dressings to create a smooth texture, prevent separation and extend shelf life.

Commonly used emulsifiers in modern food production include mustard, soy and egg lecithin, mono-and diglycerides, polysorbates, carrageenan, guar gum and canola oil. Lecithin in egg yolks is one of the most powerful and oldest forms of an animal-derived emulsifier used to stabilize oil in water. These ingredients are required by law to be included on a food’s ingredient label. Emulsifiers can disrupt the tight seal called tight junctions formed by the intestinal tract lining, enabling gut bacteria to cross and gain access to nearby immune cells, promoting metabolic toxemia.

Even though these ingredients are on the Generally Recognized As Safe (GRAS) list , many have not been thoroughly tested. Testing can occur if an ingredient is found to causes a health problem.

Conclusions: The mice study presented below was concluded by the co-author, Andrew Gewirtz, PhD, as saying, “We suspect some emulsifiers act like detergents, upsetting the friendly bacteria in the microbiota, which triggers low-grade inflammation and causes excess  eating and weight gain”. A follow-up study suggested the changes in gut bacteria from emulsifiers could trigger bowel cancer;  however, more recent findings confirmed that emulsifiers remained safe at the estimated exposure levels. However, based on the study, the use of these emulsifiers may need some revision.

Bottom Line:  The current use of emulsifiers in the food production system may affect the health of the microbiome and parameters of the metabolic syndrome. This in turn can contribute to a higher risk of several chronic diseases, namely obesity and/or diabetes type 2. Consumers are encouraged to read labels and consume less highly processed foods and substitute more minimally processed foods to prevent these occurrences.

UPDATE: Source: Medical News Today, August, 2020

A new study has found that people with metabolic syndrome, which refers to a cluster of conditions that increase a person’s risk of cardiovascular issues, are more likely to have worse COVID-19 outcomes — including requiring ventilation and death.

The research, which appears in the journal Diabetes Care, August, 2020, provides further information on the underlying risk factors that affect the severity of COVID-19.

CLICK HERE.