The Glycemic Response: Sugar and Your Body

Blood sugar control is the goal of people who are either prediabetic or diabetic (type 1 or 2).

Why are high blood sugar levels bad for you? Glucose is precious fuel for all the cells in your body when it’s present at normal levels. But it can behave like a slow-acting poison and become a “silent killer.” when the normal rises.

  • High sugar levels slowly erode the ability of cells in your pancreas to make insulin. The organ overcompensates and insulin levels stay too high. Over time, the pancreas is permanently damaged. Insulin resistance may ensue.
  • High levels of blood sugar can cause changes that lead to a hardening of the blood vessels, what doctors call atherosclerosis.

Almost any part of your body can be harmed by too much sugar. Damaged blood vessels cause problems such as:

  • Kidney disease or kidney failure, requiring dialysis
  • Strokes
  • Heart attacks
  • Vision loss or blindness
  • Weakened immune system, with a greater risk of infections
  • Erectile dysfunction
  • Nerve damage, also called neuropathy, that causes tingling, pain, or less sensation in your feet, legs, and hands
  • Poor circulation to the legs and feet
  • Slow wound-healing and the potential for amputation in rare cases

Keep your blood sugar levels close to normal to avoid many of these complications.

What is the Glycemic Response?

The glycemic response is the rate, magnitude, and duration of the rise in blood glucose that occurs after a particular food or meal is consumed. It is affected by both amount and type of carbohydrate eaten and the amount of fat and protein in that food or meal.

Refined sugars and starches generally cause a greater glycemic response than refined carbohydrates that contain fiber. This is because sugar and starches alone leave the stomach quickly and are rapidly digested and absorbed, causing a sharp, swift rise in blood sugar. For example, when you drink a can of soda or eat a slice of white bread on an empty stomach your blood sugar increases within minutes. Eating a high fiber food causes a slower, lower increase in blood sugar. The presence of fat and protein also slows stomach emptying, and therefore foods high in these macro- nutrients generally causes smaller glycemic response than foods containing sugar or starch alone. For example , ice cream is high in sugar but also contains fat and some protein , so it causes a smaller rise in blood glucose than sorbet which contains sugar but no fat or protein. In fact, the GI for a baked potato is higher than for a serving of ice cream (due to the fat and sugar).

What is the Glycemic Index? (GI) 

Glycemic index is its ranking of how a certain food effects blood glucose compared to the response of an equivalent amount of carbohydrate from a reference food such as, white bread or pure glucose. The reference food is assigned a value of 100 and the values for other foods are expressed relative to this. Foods that have a glycemic index of 70 or more compared to glucose are considered high glycemic index foods those with an index of less than 55 are considered a low glycemic index food.

What is the Glycemic Load? (GL)

Glycemic load (GL) is a method of assessing glycemic response that takes into account both the glycemic index of the food and the amount of carbohydrate in a typical portion. To calculate glycemic load, the grams of carbohydrate in a serving of food are multiplied by that foods glycemic index expressed as a percentage.  A glycemic load of 20 or more is considered high, where a value of less than 11 is considered low.

For example: A raw carrot provides about 7 grams of carbohydrate and has a glycemic index of 47. It’s glycemic load (GL) is calculated as:

7 X 47 = 329.

329 / 100 = 3.29

Glycemic load = 3.29 

Bottom Line: Some high-GI foods, such as baked potatoes and French bread, are good sources of a number of nutrients. Just because a food has a high glycemic index doesn’t mean it should not be used as part of a balanced diet. Adjusting food choices toward selection of mainly  low GI foods is most helpful for people attempting to prevent or control type 2 diabetes.

Type 2 diabetes is usually diagnosed using the: Glycated hemoglobin (A1C) test. This blood test indicates your average blood sugar level for the past two to three months. Normal levels are below 5.7 percent, and a result between 5.7 and 6.4 percent is considered prediabetes. It is important to see your physician who then may refer you to a certified diabetes educator or registered dietitian. Weight and carbohydrate control appears to be the best approach to deal with or even prevent diabetes type 2.  

The following links can further discuss the glycemic response as well as provide a table of the glycemic index and glycemic load of 100 foods tested.

CLICK HERE. and HERE

Source:

The American Diabetes Association

Nutrition. Smolin and Grosvenor, Wiley, 3rd Edition

Nutrition Now. Judith E. Brown, Wadsworth Centage Learning, 7th Edition

 

Chronic Inflammation: Understanding the “Cytokine Storm”

The leading causes of death among Americans are slow developing, lifestyle-related chronic diseases. This includes diabetes, heart disease,  stroke, cancer, hypertension or high cholesterol levels. Diet can often be (but not always) the underlying condition reflected as obesity.  Obesity is now considered to be a major risk factor for complications of COVID-19 infections.

A previous post  explains the role of diet in this occurrence. The post was written before the  co-morbidities   (underlying conditions) were associated with inflammation and severe COVID infections. The following well written article was initially published in The Conversation and succinctly explains how the role of inflammation can contribute to severe COVID and death often described as the “cytokine storm”.

CLICK HERE.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Food Additives and the Metabolic Syndrome

 

What is the metabolic syndrome?

The metabolic syndrome is cluster of conditions that increase the risk of heart disease, stroke, and diabetes.

Metabolic syndrome includes high blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol levels. The syndrome increases a person’s risk for heart attack and stroke. Weight loss, exercise, a healthy diet, and smoking cessation can help. Medications may also be prescribed.

In the current study presented, the results support the emerging concept that perturbed host–microbiome interactions resulting in low-grade inflammation can promote obesity and its associated metabolic effects. Moreover, they suggest that the broad use of emulsifying agents might be contributing to an increased societal incidence of obesity/metabolic syndrome and other chronic inflammatory diseases.

Emulsifiers as a food additive act as detergents to  reduce stickiness, control crystallization and prevent separation. They are commonly used in many processed foods such as mayonnaise, ice cream, peanut butter, chocolate, salad dressings to create a smooth texture, prevent separation and extend shelf life.

Commonly used emulsifiers in modern food production include mustard, soy and egg lecithin, mono-and diglycerides, polysorbates, carrageenan, guar gum and canola oil. Lecithin in egg yolks is one of the most powerful and oldest forms of an animal-derived emulsifier used to stabilize oil in water. These ingredients are required by law to be included on a food’s ingredient label. Emulsifiers can disrupt the tight seal called tight junctions formed by the intestinal tract lining, enabling gut bacteria to cross and gain access to nearby immune cells, promoting metabolic toxemia.

Even though these ingredients are on the Generally Recognized As Safe (GRAS) list , many have not been thoroughly tested. Testing can occur if an ingredient is found to causes a health problem.

Conclusions:
The mice study presented below was concluded by the co-author, Andrew Gewirtz, PhD, as saying, “We suspect some emulsifiers act like detergents, upsetting the friendly bacteria in the microbiota, which triggers low-grade inflammation and causes excess  eating and weight gain”. A follow-up study suggested the changes in gut bacteria from emulsifiers could trigger bowel cancer;  however, more recent findings confirmed that emulsifiers remained safe at the estimated exposure levels. However, based on the study, the use of these emulsifiers may need some revision.

Bottom Line:  The current use of emulsifiers in the food production system may affect the health of the microbiome and parameters of the metabolic syndrome. This in turn can contribute to a higher risk of several chronic diseases, namely obesity and/or diabetes type 2. Consumers are encouraged to read labels and consume less highly processed foods and substitute more minimally processed foods to prevent these occurrences.

UPDATE: Source: Medical News Today, August, 2020

A new study has found that people with metabolic syndrome, which refers to a cluster of conditions that increase a person’s risk of cardiovascular issues, are more likely to have worse COVID-19 outcomes — including requiring ventilation and death.

The research, which appears in the journal Diabetes Care, August, 2020, provides further information on the underlying risk factors that affect the severity of COVID-19.

CLICK HERE.

A Better Idea? Pastured Pigs

The other day, I cooked a pork tenderloin (at low heat) and was surprised to find the meat “stringy” and not very tender. We had not found that a few years ago when we had used the very same recipe. What has happened to the perfect pig?

Pork had been the meat of choice since Colonial Days in the Plymouth Colony (circa 1623). The dense American forests were ideal for raising pigs. They were allowed to remain “wild” and roam freely most of the year with only penning them in the winter.  They were “finished” on corn that made the flesh firm but tender and they gained weight quickly. Pigs were more efficient than cattle for meat, so cattle were more used for milk, butter, cheese and plowing.

Excerpts from an article from U.S. News and World Report (August 15, 2005) offers some reasons.

“Pigs aren’t porky anymore. Instead, they are as lanky as marathon runners.  However, today’s pork roasts all too often don’t taste good and the meat is dry.” Through breeding practices, searching for a leaner pig began back in the 1970’s when customers began to demand low fat food products that satisfied the flawed low fat movement for heart health. “This alarmed pork producers who launched a now familiar campaign, “The Other White Meat” attributable to pork that suggested that it was just as lean as chicken. It wasn’t just hype. According to 2005 standards, “supermarket pork is 31% lower in fat than it was 20 years ago.”

“All during the 80’s and 90’s, animal scientists continued to try to say that they could get a leaner hog with more muscle” said a meat scientist at Iowa State University. “They lost the taste, they lost the moisture content”, he said.

So what is  the perfect pig?  It depends on the time frame. The feral pig was first domesticated in the Middle East and central Asia 9,000 years ago. It was brought to America in 1493 on Columbus’s second voyage. The 1900 pig was bigger to provide lard that was highly prized at the time. Some pigs topped 2,000 pounds. The typical market pig today is lean and muscled, with a market weight of from 275 to 300 pounds.

Everyone has their own motivation when it comes to changing their diet; to lose weight, to be healthier, to eat or reduce meat consumption, to address environmental or animal welfare, and to enjoy great tasting food.

For some of us, the perfect pig is a “happy pig”.  Fat or lean – the most important aspect is how the animals are treated by us  when they are in our care (my opinion).

Being an “ethical omnivore” is about an attitude towards what you consume and the effect it has on you and others. It also involves how we treat the animals we choose to consume or not to consume. We as “ethical omnivores ” need to know where our food comes from and respect the welfare of the animals in exchange for what they provide for us.

A better idea rather than manipulating their fat content in the ethical treatment of animals may be seeking out and encouraging pastured pigs that are raised with animal welfare standards including compassion and dignity in their own natural environments.  There they can receive better diets that are more suited to their physiological needs rather than attempting to alter their size and fat content artificially to please the food industry profits. After some soul searching combined with my love for animals, I think pork will come off our menu for a long time.

A good book to read about animal-human relationships is Some We Love, Some We Hate, Some We Eat by Hal Herzog: Why It’s So Hard to Think Straight About Animals. Hal Herzog is recognized as one of the world’s leading experts on human-animal relations. He is a professor of psychology at Western Carolina University and lives in the heart of the Great Smoky Mountains.

“The greatness of a nation and its moral progress can be judged by the way its animals are treated.”

Mohandas Gandhi

 

 

 

 

 

 

 

 

 

 

 

 

 

Plastics in our Food?

The Great Pacific Garbage Patch?

Some sensible, reasonable advice to help to avoid a growing problem of  food contamination from the packaging of mainly processed foods. The main article below particularly points to the ever-growing problem of micro-plastics in our oceans.

6 Ways to Use Less Plastic

Source: Consumer Reports

While it’s practically impossible to eliminate plastic from modern life, there are a number of steps you can take right now to cut back.

Do: Drink tap water.
Don’t: Rely on bottled water.

Water from plastic bottles has about double the microplastic level of tap water on average, according to a 2018 study published in the journal Frontiers in Chemistry. So unless your tap water is contaminated with unsafe elements, such as lead, it’s probably best to drink tap. Fill up a metal reusable bottle for when you go out. You can always filter your tap water. Depending on the filter, that may further reduce microplastic levels. (Check CR’s ratings of water filters.)

Do: Heat food in or on the stove, or by microwaving in glass.
Don’t: Microwave in plastic.

Some heated plastics have long been known to leach chemicals into food. So if you’re warming up food, use a pan in the oven or on the stove, or if you’re microwaving, use a glass container. Also, avoid putting plastics in the dishwasher because of the high heat involved in cleaning.

Do: Buy and store food in glass, silicone, or foil.
Don’t: Store food in plastic, especially plastic that may contain harmful chemicals.

The American Academy of Pediatrics has said that plastic food containers with the recycling codes 3, 6, and 7 may contain potentially harmful chemicals, unless they’re labeled “biobased” or “greenware.” Don’t store food in these types of containers. Instead, use containers made of glass or silicone, or wrap your food in aluminum foil. If you’re storing food in or eating food out of plastic containers, know that plastics with recycling codes 1 and 2 are more likely to be recyclable—though they are usually recycled into lower-quality plastics. And there still may be harmful or unknown chemicals in any type of plastic.

Do: Eat fresh food as much as possible.
Don’t: Rely on processed food wrapped in plastic.

The more processed or packaged a food is, the higher the risk that it contains worrisome chemicals. Food cans are often lined with bisphenol A (or similar compounds). Buy fresh food from the supermarket, and—as much as possible—try to use refillable containers if your market allows. (Of course, with shopping made difficult by the coronavirus pandemic, prioritize your health and shop however is most feasible and safest.) Certain markets let you fill up cardboard or reusable containers with bulk items and weigh them, or you can use your own mesh bags for produce. Raw meat and fish need to be kept separate for safety reasons, but ask the store fishmonger or butcher to wrap these foods in wax paper instead of plastic. Take cloth—not plastic—reusable bags to the store to take your groceries home.

Do: Vacuum regularly.
Don’t: Allow household surfaces to get dusty.

The dust in your house could be loaded with microplastics and chemicals that are found in plastic, such as phthalates. Cleaning up dust may help reduce the amount of plastics you inhale, especially if you are stuck inside for long periods of time during a period of social distancing. CR recommends vacuuming regularly with a HEPA filter, which is best for trapping dust. (Check CR’s ratings of vacuums.)

Do: Work with your community.
Don’t: Assume your impact is limited to what you do in your personal life.

Legislation to limit the use of single-use plastics and plastic production may pull the biggest levers, but joining forces with community-level recycling groups can truly make a difference. Look for so-called zero-waste groups, which can offer guidelines for how to recycle or compost all your garbage—and which lobby for local rules that can restrict throwaway items. When possible, shop at markets that source goods locally, so they don’t require as much packaging and shipping. Seek out groups such as Upstream, a nonprofit working to create reusable takeout packaging for restaurants. And when possible, educate yourself about and support any city, county, and state legislation limiting single-use plastic

CLICK HERE for the main article.

 

Getting your protein from plants: A recipe for longevity?

Question: Does plant or animal protein affect mortality and/or longevity?

A study found that for every 3% of a persons daily energy intake coming from plant protein instead of animal protein reduces a person’s risk of premature death by 10%.

For this study the researchers analyzed dietary data from more than 237, 000 men and 179, 000 women gathered between 1995 and 2011 as part of a long-term study on eating patterns and health. During 16 years of follow-up, a pattern emerged where plant protein intake appeared to reduce risk of early death. Every 10 grams of plant for animal protein swapping per 1000 calories resulted in a 12% lower risk of death for men and 14% for women, the finding showed.

Bottom Line: The findings provide evidence that dietary modification in choice of protein sources may influence cardiovascular health and longevity.

Taking red meat out of your diet can be beneficial, but only if you swap for a healthy substitute, said a lead researcher from the US National Cancer Institute. For example, replacement of 3% energy from egg protein or red made protein with plant protein such as whole grains or cereals resulted in a protective Association for overall mortality, the researcher said on the other hand replacement of 3% energy from egg protein or red meat protein with other foods such as sugar sweetened beverages may or may not result in a reduction in mortality.

There are many reasons why choosing plant protein over animal protein could help extend your life; meat protein tends to come with higher levels of saturated fat, cholesterol, sodium and other nutrients that aren’t very good for your health. For example, one ounce of red meat mixed with whole wheat pasta and veggies would provide much less saturated fat than a 9 ounce steak

On the other hand, plant proteins come with loads of fiber , antioxidants, and other compounds like vitamins and minerals that add to the nutrient density along with lesser calories as fat than in some meat products (processed meat in particular).

The researchers also added that there might be something specific about the products formed from the breakdown of animal-based protein that could cause arteries to grow harder or inflammation to occur. In 2011, researchers from the Cleveland Clinic demonstrated that meat eaters produced a metabolite that promotes heart disease called Trimethylamine-N-Oxide or TMAO. Of great interest, TMAO was not elevated in vegans who were asked to meet eat a meat meal for the purposes of the study. .

Huang, Jiaqu, et al. JAMA Intern Med. Published online July 13, 2020.

 

Is DNA Your Destiny?

Thinking of getting one of those DNA testing kits?  Aside from the Ancestry tests, the tests for your future health risks may be questionable and at this point you may want to save your money. Here is why.

A new outlook on genetics is called epigenetics  and involves the concept of environmental factors (including diet) affecting how genes are expressed or inhibited. Thanks to this relatively new science, we now know that experiences of previous generations may show up in your health and well-being. Many of the risks for chronic diseases – including obesity, diabetes type 2, high blood pressure, heart disease and dementia can be traced back to your biological roots and the experiences your parent and even grandpaents had. Similarly, the food you eat may affect your children and grandchildren.

Is Your DNA Your Destiny?

Gene Expression: the process by which a cell converts the genetic code into RNA and protein

Epigenetics: the study of heritable changes in gene function that occur without a change in the DNA sequence itself

DNA Methylation: A chemical reaction that occurs in a cell when a methyl group attaches to DNA, changing the expression of the gene to which it is attached.

Methyl Group: A type of molecular structure that occurs in many compounds, CH3, for example.

Methyl Donor: Nutrients, like folate and vitamin B12 that when metabolized can donate methyl groups during the process.

To fully illustrate the epigenetic process, one must tell the story of the agouti gene.

The Result of Methylation

Methylation Effects in the DNA

Both these mice have the gene called the agouti gene that tends to produce fat, yellow pups, so we want to silence the expression of the gene if possible. There is a way.  The mom of the brown mouse was fed B vitamins which silenced the gene. This produced brown pups with normal appetites resulting in a thin, healthy mouse.

Without altering the genomic structure, agouti moms were then able to produce healthy brown pups of normal weight and less prone to diseases. Even more surprising, when the offspring become mothers themselves, their babies can also be healthy, even without further vitamin supplementation. The yellow variant had been silenced, and that muted effect was inherited by the offspring. 

How did this occur?  Some nutrients silence genes by providing methylation (adding a methyl group (CH3); others activate genes by inhibiting methylation. It’s like throwing a wrench into the DNA to stop the expression of a gene or removing the wrench to allow the expression of the gene. The B vitamins acted as methyl donors that caused methyl groups to attach more frequently to the agouti gene in utero, inhibiting its expression. (See the black dots in the diagram above).   Silence or inhibiting depends on what the gene does: e.g., silencing a gene that stimulates cancer growth is beneficial; silencing a gene that suppresses cancer growth would be harmful.

In any case, your lifestyle choices may play a role in your future health status.

It must be remembered that with any new concept, doubts and skepticism will occur. It must be recognized that we are not mice or lab rats, but the same effect has been shown by studying human interactions and is needed for more research to examine this interesting hypothesis. The   implications are enormous in that we may be able to improve our health status by choosing healthy habits and lifestyles such as diet, exercise, stopping smoking, for example.

“The packaging of the gene may be as important as, or even more important than, the gene itself, and these epigenetic changes are predominantly influenced by environmental factors.” The Cancer Code, A Revolutionary New Understanding of a Medical Mystery Dr. Jason Fung, 2020.

Nutrition News: No Nonsense

Are those eggs OK to eat? 

Too many of us end up throwing out food that is still perfectly safe to eat. Eggs are often on the top of the list of things people think go bad quickly. But eggs are safe to eat up to five weeks after the sell by date. If you’re curious about when those eggs were packed just look at the number under the sell by date, the three-digit number in the middle.

The problem with potassium.

Many people load up on bananas and potatoes because they are high in potassium, which can help lower blood pressure. But more isn’t always better. Too much potassium can cause irregular heartbeat and other side effects. While the National Institutes of Health has not released an upper limit for potassium, the supplements in the US do not contain more than 99 milligrams. Taking more potent forms can have serious adverse side effects including confusion, temporal paralysis, low blood pressure, weakness, and coma.

Reduce Your Risk of Stroke

What is the biggest benefit of getting enough protein? If you said building muscles, you’d be close, but it might not be the biggest benefit. Recent studies show people who ate the most protein had higher levels of HDL ( good cholesterol) and those who eat the most protein (not including red meat ) were 20% less likely to suffer a stroke than those with the lowest intake. What’s more, people who ate more protein and fewer carbohydrates had better numbers for blood pressure, LDL cholesterol, and triglycerides.

Bacon as Bad as Smoking?

Is that slice (or two or three) of bacon on your BLT as dangerous as smoking a cigarette? Processed meats like bacon and cold cuts are listed as a Group One carcinogen, the same as smoking or asbestos. But that doesn’t mean they’re equally as dangerous. The classification reflects the strength of evidence linking processed meats – think: bacon, sausages, hot dogs, jerky, and cold cuts to cancer risk. Basically, any meat that’s been tweaked to enhance the flavor or improved preservation by salting, curing, fermentation or smoking is considered processed. Just one 0.75 ounces of bacon (about two slices a day) is linked to an 18% greater risk of colorectal cancer. That’s the equivalent of 1 hot dog or a couple slices of cold cuts. While it isn’t a good idea to load up on these foods, they’re often high in saturated fat and salt too, let’s put the risk in perspective. The lifetime risk of an average American of developing colorectal cancer is 5%. An 18% increase raises that number to about 6%, so an occasional ballpark dog or B LT should be fine.  Important note: simply choosing nitrate-free meats may not reduce your risk of cancer. High temperature cooking methods like pan frying and grilling may produce more carcinogens in meat. Choosing lower temperature cooking methods like braising or roasting may reduce your risk. Ever tried cooking bacon in the oven? Works well!

Zinc can help boost your immunity as you age.

A new study showed that 30% of nursing home residents have low blood levels of zinc, and those with low levels were at significantly higher risk of pneumonia. Ensuring adequate zinc consumption could reduce chances of deadly infections. Zinc helps to improve the function of T-cells, a special type of white blood cell that targets and destroys invading bacteria and viruses. Zinc supplementation not only increased the number of T- cells, but it improved effectiveness, too. Get more zinc in your diet with shellfish, pork, cashews, peanuts, and chickpeas.

SOURCE:

19 Health and Nutrition Secrets that Can Change Your Life: Tufts University Health and Nutrition Letter

Some Good News for a Vaccine?

Coronavirus Spikes

In  case you wonder why a food blogger like me is posting this article, I taught an infectious disease course for a number of years, worked in academia in Microbiology and Immunology, and antibody production in the body was part of my doctoral dissertation.

I love this article for the fact that it is often hard to find facts that you can trust – so I hope that this brings us some hope for a successful vaccine ASAP against Covid-19.

CLICK HERE.

Vitamin C and Respiratory Infections

What Do We Know About Vitamin C?

Vitamin C is an essential nutrient in humans. Without it we die.

Most animals internally produce their own vitamin C; humans do not so we need to obtain it from the diet or other external sources  (supplements). It is a water-soluble vitamin and cannot be stored in the body.

Severe deficiency may develop within three weeks of very low intake. This can result in a sub-clinical form of scurvy that can be manifested in increased susceptibility to infections. This is often shown initially by easy bruising.

Diets lacking in fruits and vegetables (such as a low-carbohydrate diet) often do not provide enough vitamin C.

Functions of vitamin C

  • Needed for manufacture of collagen
  • Helps the body fight infections, repair wounds
  • Act as antioxidant
  • Enhances iron absorption.

Primary food sources:

Fruits: guava, oranges, lemons, limes, strawberries, cantaloupe, grapefruit, kiwi fruit

Vegetables: broccoli, green and red peppers, collards, tomato, potatoes, ready to eat cereals (fortified)

FYI: The RDA for vitamin C is 15-75 mg/d for children, 75 mg/d for adult women, 90 mg/d for adult men, and 85 to 120 mg for pregnant and breastfeeding women.

The Tolerable Upper Limit is 2000 mg/d. Oral Intakes of 1 gram or more a day can cause nausea, cramps, and diarrhea and may increase the risk of kidney stones.

Impact on Infections

Some studies show that in common infectious diseases, supplemental vitamin C lessens the severity and duration of symptoms.

In severe respiratory diseases such as bronchitis or pneumonia, vitamin C has been shown to reduce symptoms and shorten hospital stays. Some studies report rapid clearance on chest x-rays of patients with lung infections, following intravenous vitamin C treatment.

From the Linus Pauling Institute (LPI) at Oregon State University comes this:

“March 13, 2020 – The Linus Pauling Institute is closely watching the clinical trials with intravenous (IV) vitamin C and COVID-19-related pneumonia with great interest. However, there currently are no available data to show vitamin C can prevent or successfully treat COVID-19 infections. Once the trial data are available for review, the LPI will comment on the efficacy of IV vitamin C in COVID-19.

In 1970, Dr. Linus Pauling, Nobel Prize winner,  published Vitamin C and the Common Cold, a book that revolutionized the way the world viewed vitamin C and infectious disease. Dr. Pauling believed that increasing the daily dose of vitamin C could help the body mount a strong immune response when confronted with a respiratory infection.

Many people worldwide have reported better health after taking large amounts of vitamin C. To date, clinical trials have shown that vitamin C supplements can shorten the duration of the common cold. However, there are no data to suggest that vitamin C supplements can stop respiratory infections in the general population.  Results from trials with participants undergoing heavy physical activity indicate a benefit of oral vitamin C on common cold incidence. There are no such trials on influenza or coronavirus.

The LPI continues to advocate for rigorous research on both oral and IV vitamin C for treating both inflammation and infection. Yet, the facts are that there have been few rigorous studies on vitamin C and respiratory infections. Clinical trials with IV vitamin C and coronavirus-related pneumonia are currently underway in China. These trials are of great interest to the LPI, and we will monitor them closely.

Meanwhile, the LPI recommends taking these steps to support a healthy immune system: Eat a healthy diet and ensure that you meet the recommended intakes of all micronutrients, especially vitamins A, C, D, E, as well as zinc

Oregon State University has established a COVID-19 website to provide detailed and updated information; links to OSU, local, state and federal resources; and some frequently asked questions. Please regularly check this website for important updates.”

Source: Nutrition Now, Brown, Seventh Edition

Linus Pauling Institute, Oregon State University